What is NAD+

NAD+ (Nicotinamide Adenine Dinucleotide) is a coenzyme, a molecule that participates in hundreds of reactions in cells. Its main role is electron transfer in energy metabolism.

Simply put: NAD+ helps cells produce energy from food (glucose, fats, proteins) through mitochondria.

NAD+ and Aging

NAD+ (Nicotinamide Adenine Dinucleotide) is a coenzyme, a molecule that participates in hundreds of reactions in cells. Its main role is electron transfer in energy metabolism.

Simply put: NAD+ helps cells produce energy from food (glucose, fats, proteins) through mitochondria.

As we age, NAD+ levels in the body decline, which leads to:

• decreased cellular energy production,
• impaired mitochondrial function,
• reduced DNA repair and antioxidant defenses,
• lower activity of sirtuins — proteins that slow down aging processes.

In short, a drop in NAD+ is directly linked to cellular aging.

NAD+ Metabolism

NAD+ metabolism refers to the processes through which NAD+ is:

• Synthesized from precursors (e.g., niacin, nicotinamide, NMN, tryptophan).
• Used in reactions (e.g., oxidative metabolism, PARP enzymes, sirtuins).
• Regenerated back into NAD+ after use.

Maintaining a balance between NAD+ synthesis and usage is crucial, otherwise cells age faster.

Why It Matters for Anti-Aging

• Better mitochondrial function: more energy, less age-related damage.
• Active sirtuins: regulate genes responsible for longevity and cell repair.
• DNA repair and oxidative stress protection: NAD+ participates in enzymes that fix DNA and combat damage.

How Supplements Affect NAD+ Metabolism

• Niacin (B3): a precursor for NAD+.
• NAD+ in supplements: may directly increase NAD+ levels.
• Resveratrol and other sirtuin activators: work together with NAD+ to “turn on” anti-aging genes.

Thus, a supplement with NAD+ + B3 + Resveratrol is designed to support cellular energy, DNA repair, and sirtuin activation — key mechanisms for slowing aging.